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Howard: Publications

Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats.
Beardsley PM, Pollard GT, Howard JL, Carroll FI.
Psychopharmacology (Berl). 2010 Jun;210(2):189-98. Epub 2010 Apr 7.

Outcome after decompressive craniectomy for the treatment of severe traumatic brain injury.
Howard JL, Cipolle MD, Anderson M, Sabella V, Shollenberger D, Li PM, Pasquale MD.
J Trauma. 2008 Aug;65(2):380-5; discussion 385-6.PMID: 18695475 [PubMed - indexed for MEDLINE]

HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages.
Dowling D, Nasr-Esfahani S, Tan CH, O'Brien K, Howard JL, Jans DA, Purcell DF, Stoltzfus CM, Sonza S.
Retrovirology. 2008 Feb 4;5:18.


Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats.
Beardsley PM, Howard JL, Shelton KL, Carroll FI.
Psychopharmacology (Berl). 2005 Nov;183(1):118-26. Epub 2005 Oct 22.PMID: 16184376 [PubMed - indexed for MEDLINE]


Sequential extraction analysis of heavy metals in sediments of variable composition using nitrilotriacetic acid to counteract resorption.
Howard JL, Vandenbrink WJ.
Environ Pollut. 1999 Sep;106(3):285-92.

Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
Carroll FI, Pawlush N, Kuhar MJ, Pollard GT, Howard JL.
J Med Chem. 2004 Jan 15;47(2):296-302.PMID: 14711303 [PubMed - indexed for MEDLINE]

Selectively reduced tat mRNA heralds the decline in productive human immunodeficiency virus type 1 infection in monocyte-derived macrophages.
Sonza S, Mutimer HP, O'Brien K, Ellery P, Howard JL, Axelrod JH, Deacon NJ, Crowe SM, Purcell DF.
J Virol. 2002 Dec;76(24):12611-21.PMID: 12438587 [PubMed - indexed for MEDLINE]


One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
Ralley FE, Berta D, Binns V, Howard J, Naudie DD.
Department of Anesthesia and Perioperative Medicine, University of Western Ontario, London, ON, Canada.
Erratum in: Clin Orthop Relat Res. 2010 May;468(5):1447.



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